October 7, 2025
Dr. Edward Group, DC
How NAD+ Supplements Can Help Boost Energy
If you do everything you “should” be doing to keep your energy levels up—eat a balanced diet, get
enough sleep, move your body, practice stress management—and still feel exhausted, it could be a sign that
your internal energy systems need support.
One of the most important molecules involved in cellular energy is NAD+ (nicotinamide adenine dinucleotide), which
helps your cells generate and sustain energy. Your natural levels of NAD+ decline with age and can leave you feeling
tired, sluggish, or mentally foggy.[1]
If you’ve been searching for a science-backed way to support your body’s natural energy production, a
NAD+ supplement may be the answer. Let’s dive into everything you need to know about NAD+ for energy.
What Does NAD+ Do for Energy?
Every cell in your body relies on mitochondria to convert nutrients from food into usable energy, which includes a
molecule called ATP (adenosine triphosphate). NAD+ acts as a coenzyme in this process, enabling your mitochondria to
produce ATP efficiently.
When NAD+ levels are sufficient, you may feel more physically resilient, mentally sharp, and emotionally
balanced.[2]
But when NAD+ becomes depleted, even basic processes start to feel harder. You may notice persistent fatigue or a
general sense of burnout.
By supporting healthy NAD+ levels with a supplement, you’re helping to restore your body’s natural ability to
create and sustain energy deep within your cells.
Do NAD+ Supplements Work for an Energy Boost?
Unlike stimulants such as caffeine, which temporarily spike your energy by activating the nervous system, NAD+ works
at the foundational level. Studies have shown that increasing NAD+ levels can support mitochondrial function,
enhance cellular repair, and improve metabolic efficiency.[3] In simpler terms:
your cells work better, so you feel
better. And that includes having more consistent, sustainable energy.
Many people who begin NAD+ supplementation can experience subtle but meaningful improvements, including sharper
mental focus throughout the day and improved physical endurance, especially during exercise or busy periods.[4],[5]
How Much NAD+ Is Needed Per Day for Energy?
The amount of NAD+ needed per day for energy varies from person to person. Factors such as age, metabolism,
lifestyle, and overall health can influence how well your body absorbs and utilizes NAD+.
The serving size on your NAD+ supplement label is a good place to start. Just be sure to check that the supplement
doesn’t have any unnecessary fillers or artificial ingredients that could dilute the formula or hinder
absorption.
It’s always a good idea to consult with a healthcare professional before beginning NAD+ supplementation. They
can provide personalized guidance based on your unique needs and help ensure safety alongside other treatments or
medications you might be using.
Consistency is the most important thing. Although you won’t feel an immediate energy boost, like you would
after drinking coffee, regular NAD+ supplementation can give you gradual, lasting results.
Who Can Benefit Most From NAD+ for Energy?
NAD+ supplementation can be especially helpful for women between 30 and 50 who are experiencing natural hormone
shifts and the demands of a busy life. If you find yourself juggling multiple responsibilities, experiencing
burnout, or simply struggling to keep up with your usual energy levels, NAD+ may offer the cellular support your
body needs.
Athletes and active individuals can also benefit, as NAD+ helps enhance endurance and recovery.[6] Even if you’re
recovering from illness, overwork, or lifestyle factors that have depleted your energy reserves, supporting your
NAD+ levels can help you rebuild strength from the inside out.
Are There Any NAD Supplement Side Effects?
NAD+ supplementation is generally well tolerated by most people, as NAD+ is a natural molecule your body already
produces.[7] The risk of serious side effects is low when taking a high-quality
supplement.
In rare cases, some individuals may experience mild side effects such as nausea, flushing, or mild gastrointestinal
discomfort. These symptoms are usually temporary and tend to resolve as your body adjusts.
If you are pregnant, nursing, have underlying health conditions, or are taking prescription medications, it’s
best to consult with your healthcare provider before starting NAD+ supplementation.
To minimize any risks, it’s important to choose supplements made with clean, pure ingredients—free from
unnecessary fillers, artificial additives, or contaminants.
Where Can You Find a High-Quality NAD+ Supplement?
When selecting a NAD+ supplement, look for products that prioritize:
- Purity: Free from artificial additives, fillers, and contaminants
- Bioavailability: Formulas that your body can absorb and use effectively
-
Third-party testing: Independent verification to ensure safety, potency, and ingredient
accuracy
Global Healing’s NAD+ supplement combines these qualities with MicroSomal®
Technology for the purest, most bioavailable third-party tested NAD+ supplement on the market.
Boost Energy Levels with a MicroSomal® NAD+ Supplement
Feeling tired as you get older isn’t something you just have to accept. When you support your body’s
natural energy systems at the cellular level, you can bring some youthful vitality back into your life.
Global Healing’s MicroSomal® NAD+ is a clean formula made with bioidentical NAD+, an advanced delivery
system, and rigorous quality testing.
Shop MicroSomal® NAD+ to experience the difference it can make for your energy
levels.
†Results may vary. Information and statements made are for education purposes and are not intended to replace
the advice of your doctor. If you have a severe medical condition or health concern, see your physician.
References (7)
- McReynolds, M. R., Chellappa, K., & Baur, J. A. (2020). Age-related NAD+ decline. Experimental
Gerontology, 134, 110888. https://doi.org/10.1016/j.exger.2020.110888 - Zhao, Y., Zhang, J., Zheng, Y., Zhang, Y., Zhang, X. J., Wang, H., Du, Y., Guan, J., Wang, X., & Fu, J.
(2021). NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage
and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway.
Journal of Neuroinflammation, 18(1). https://doi.org/10.1186/s12974-021-02250-8 - Eisner, V., Picard, M., & Hajnóczky, G. (2018). Mitochondrial dynamics in adaptive and
maladaptive cellular stress responses. Nature Cell Biology, 20(7), 755–765. https://doi.org/10.1038/s41556-018-0133-0 - Tarantini, S., Valcarcel-Ares, M. N., Toth, P., Yabluchanskiy, A., Kiss, T., Ballabh, P., Farkas, E., Baur,
J., Sinclair, D., Csiszar, A., & Ungvari, Z. (2020). Nicotinamide mononucleotide (NMN) supplementation
rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves
cognitive function in aged mice. The FASEB Journal, 34(S1), 1–1. https://doi.org/10.1096/fasebj.2020.34.s1.05763 - Perryman, R., Chau, T. W., De-Felice, J., O’Neill, K., & Syed, N. (2024). Distinct Capabilities in
NAD Metabolism Mediate Resistance to NAMPT Inhibition in Glioblastoma. Cancers, 16(11),
2054–2054. https://doi.org/10.3390/cancers16112054 - Goody, M. F., & Henry, C. A. (2018). A need for NAD+ in muscle development, homeostasis, and aging. Skeletal
Muscle, 8(1). https://doi.org/10.1186/s13395-018-0154-1 - Freeberg, K. A., Udovich, C. C., Martens, C. R., Seals, D. R., & Craighead, D. H. (2023). Dietary
Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions. The
Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 78(12), 2435–2448.
https://doi.org/10.1093/gerona/glad106
Dr. Edward Group, DC
FOUNDER | HEALER | ADVOCATE
Dr. Group, DC is a healer and alternative health advocate, and an industry leader and innovator in the field of natural health who is dedicated to helping others. He is a registered doctor of chiropractic (DC), a naturopathic practitioner (NP), and proud alum of Harvard Business School and MIT Sloan School of Management. Dr. Group, DC is the founder of Global Healing – a mission and vision he has shared through best-selling books and frequent media appearances. He aims to spread his message of positivity, hope, and wellness throughout the world.
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